Human CD16 as a lysis receptor mediating direct natural killer cell cytotoxicity

In addition to their role in peptide antigen presentation, class I MHC proteins also play a critical role in inhibiting natural killer (NK) cytotoxicity through interaction with NK inhibitory receptors. Thus, NK cells are cytotoxic to virus-infected and tumor cells that have lost class I MHC protein...

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Main Authors: Mandelboim, Ofer, Malik, Pratap, Davis, Daniel M., Jo, Chang H., Boyson, Jonathan E., Strominger, Jack L.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC21913/
https://ncbi.nlm.nih.gov/pubmed/10318937
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