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CD28 homolog is a strong activator of natural killer cells for lysis of B7H7(+) tumor cells
The CD28–B7 family of receptor–ligand pairs regulates lymphocyte responses through costimulation and coinhibition. It includes checkpoint inhibitors, such as PD-1, which limit antitumor and antivirus T-cell responses. CD28 homolog (CD28H) and B7H7 have been identified as a receptor–ligand pair in th...
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| Publicado no: | Cancer Immunol Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548580/ https://ncbi.nlm.nih.gov/pubmed/31018957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0733 |
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