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Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response
Regulatory variants are often context-specific, modulating gene expression in a subset of possible cellular states. Although these genetic effects can play important roles in disease, the molecular mechanisms underlying context-specificity are poorly understood. Here, we identify shared quantitative...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548559/ https://ncbi.nlm.nih.gov/pubmed/29379200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0046-7 |
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