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Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens

A number of pathogens, including several human-restricted organisms, persist and replicate within macrophages (Mφs) as a key step in pathogenesis. The mechanisms underpinning such host-restricted intracellular adaptations are poorly understood, in part, due to a lack of appropriate model systems. He...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hale, Christine, Yeung, Amy, Goulding, David, Pickard, Derek, Alasoo, Kaur, Powrie, Fiona, Dougan, Gordon, Mukhopadhyay, Subhankar
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422593/
https://ncbi.nlm.nih.gov/pubmed/25946027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124307
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