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Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription

Macrophages differentiated from human induced pluripotent stem cells (IPSDMs) are a potentially valuable new tool for linking genotype to phenotype in functional studies. However, at a genome-wide level these cells have remained largely uncharacterised. Here, we compared the transcriptomes of naïve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alasoo, Kaur, Martinez, Fernando O., Hale, Christine, Gordon, Siamon, Powrie, Fiona, Dougan, Gordon, Mukhopadhyay, Subhankar, Gaffney, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519778/
https://ncbi.nlm.nih.gov/pubmed/26224331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12524
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