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Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

Alternatively activated macrophages play an important role in host defense in the context of a T helper type 2 (Th2) microenvironment such as parasitic infection. However, the role of these macrophages during secondary challenge with Th1 pathogens is poorly defined. In this study, thioglycollate-eli...

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Detalhes bibliográficos
Main Authors: Varin, Audrey, Mukhopadhyay, Subhankar, Herbein, Georges, Gordon, Siamon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808158/
https://ncbi.nlm.nih.gov/pubmed/19880493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236711
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