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Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI)

The small GTPase Rab5 is the key regulator of early endosomal fusion. It is post-translationally modified by covalent attachment of two geranylgeranyl (GG) chains to adjacent cysteine residues of the C-terminal hypervariable region (HVR). The GDP dissociation inhibitor (GDI) recognizes membrane-asso...

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Detalles Bibliográficos
Publicado en:Small GTPases
Main Authors: Edler, Eileen, Stein, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548291/
https://ncbi.nlm.nih.gov/pubmed/29065764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1371268
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