Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

Genotype imputation of the human leukocyte antigen (HLA) region is a cost-effective means to infer classical HLA alleles from inexpensive and dense SNP array data. In the research setting, imputation helps avoid costs for wet lab-based HLA typing and thus renders association analyses of the HLA in l...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Degenhardt, Frauke, Wendorff, Mareike, Wittig, Michael, Ellinghaus, Eva, Datta, Lisa W, Schembri, John, Ng, Siew C, Rosati, Elisa, Hübenthal, Matthias, Ellinghaus, David, Jung, Eun Suk, Lieb, Wolfgang, Abedian, Shifteh, Malekzadeh, Reza, Cheon, Jae Hee, Ellul, Pierre, Sood, Ajit, Midha, Vandana, Thelma, B K, Wong, Sunny H, Schreiber, Stefan, Yamazaki, Keiko, Kubo, Michiaki, Boucher, Gabrielle, Rioux, John D, Lenz, Tobias L, Brant, Steven R, Franke, Andre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Bioinformatics Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548229/
https://ncbi.nlm.nih.gov/pubmed/30590525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy443
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