Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

Genotype imputation of the human leukocyte antigen (HLA) region is a cost-effective means to infer classical HLA alleles from inexpensive and dense SNP array data. In the research setting, imputation helps avoid costs for wet lab-based HLA typing and thus renders association analyses of the HLA in l...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Degenhardt, Frauke, Wendorff, Mareike, Wittig, Michael, Ellinghaus, Eva, Datta, Lisa W, Schembri, John, Ng, Siew C, Rosati, Elisa, Hübenthal, Matthias, Ellinghaus, David, Jung, Eun Suk, Lieb, Wolfgang, Abedian, Shifteh, Malekzadeh, Reza, Cheon, Jae Hee, Ellul, Pierre, Sood, Ajit, Midha, Vandana, Thelma, B K, Wong, Sunny H, Schreiber, Stefan, Yamazaki, Keiko, Kubo, Michiaki, Boucher, Gabrielle, Rioux, John D, Lenz, Tobias L, Brant, Steven R, Franke, Andre
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Bioinformatics Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548229/
https://ncbi.nlm.nih.gov/pubmed/30590525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy443
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