Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction

Human Leukocyte Antigen class II (HLA-II) molecules present peptides to T lymphocytes and play an important role in adaptive immune responses. Characterizing the binding specificity of single HLA-II molecules has profound impacts for understanding cellular immunity, identifying the cause of autoimmu...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Wendorff, Mareike, Garcia Alvarez, Heli M., Østerbye, Thomas, ElAbd, Hesham, Rosati, Elisa, Degenhardt, Frauke, Buus, Søren, Franke, Andre, Nielsen, Morten
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438773/
https://ncbi.nlm.nih.gov/pubmed/32903714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01705
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