Directed evolution of split APEX2 peroxidase

APEX is an engineered peroxidase that catalyzes the oxidation of a wide range of substrates, facilitating its use in a variety of applications, from subcellular staining for electron microscopy to proximity biotinylation for spatial proteomics and transcriptomics. To further advance the capabilities...

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Udgivet i:ACS Chem Biol
Main Authors: Han, Yisu, Branon, Tess Caroline, Martell, Jeffrey D., Boassa, Daniela, Shechner, David, Ellisman, Mark H., Ting, Alice
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548188/
https://ncbi.nlm.nih.gov/pubmed/30848125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00919
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