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Rab5-dependent autophagosome closure by ESCRT
In the conserved autophagy pathway, autophagosomes (APs) engulf cellular components and deliver them to the lysosome for degradation. Before fusing with the lysosome, APs have to close via an unknown mechanism. We have previously shown that the endocytic Rab5-GTPase regulates AP closure. Therefore,...
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| Udgivet i: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548130/ https://ncbi.nlm.nih.gov/pubmed/31010855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811173 |
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