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Rab5-dependent autophagosome closure by ESCRT

In the conserved autophagy pathway, autophagosomes (APs) engulf cellular components and deliver them to the lysosome for degradation. Before fusing with the lysosome, APs have to close via an unknown mechanism. We have previously shown that the endocytic Rab5-GTPase regulates AP closure. Therefore,...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Zhou, Fan, Wu, Zulin, Zhao, Mengzhu, Murtazina, Rakhilya, Cai, Juan, Zhang, Ao, Li, Rui, Sun, Dan, Li, Wenjing, Zhao, Lei, Li, Qunli, Zhu, Jing, Cong, Xiaoxia, Zhou, Yiting, Xie, Zhiping, Gyurkovska, Valeriya, Li, Liuju, Huang, Xiaoshuai, Xue, Yanhong, Chen, Liangyi, Xu, Hui, Xu, Haiqian, Liang, Yongheng, Segev, Nava
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548130/
https://ncbi.nlm.nih.gov/pubmed/31010855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811173
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