Rab5-dependent autophagosome closure by ESCRT

In the conserved autophagy pathway, autophagosomes (APs) engulf cellular components and deliver them to the lysosome for degradation. Before fusing with the lysosome, APs have to close via an unknown mechanism. We have previously shown that the endocytic Rab5-GTPase regulates AP closure. Therefore,...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Zhou, Fan, Wu, Zulin, Zhao, Mengzhu, Murtazina, Rakhilya, Cai, Juan, Zhang, Ao, Li, Rui, Sun, Dan, Li, Wenjing, Zhao, Lei, Li, Qunli, Zhu, Jing, Cong, Xiaoxia, Zhou, Yiting, Xie, Zhiping, Gyurkovska, Valeriya, Li, Liuju, Huang, Xiaoshuai, Xue, Yanhong, Chen, Liangyi, Xu, Hui, Xu, Haiqian, Liang, Yongheng, Segev, Nava
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548130/
https://ncbi.nlm.nih.gov/pubmed/31010855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811173
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