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Rab5-dependent autophagosome closure by ESCRT

In the conserved autophagy pathway, autophagosomes (APs) engulf cellular components and deliver them to the lysosome for degradation. Before fusing with the lysosome, APs have to close via an unknown mechanism. We have previously shown that the endocytic Rab5-GTPase regulates AP closure. Therefore,...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Zhou, Fan, Wu, Zulin, Zhao, Mengzhu, Murtazina, Rakhilya, Cai, Juan, Zhang, Ao, Li, Rui, Sun, Dan, Li, Wenjing, Zhao, Lei, Li, Qunli, Zhu, Jing, Cong, Xiaoxia, Zhou, Yiting, Xie, Zhiping, Gyurkovska, Valeriya, Li, Liuju, Huang, Xiaoshuai, Xue, Yanhong, Chen, Liangyi, Xu, Hui, Xu, Haiqian, Liang, Yongheng, Segev, Nava
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548130/
https://ncbi.nlm.nih.gov/pubmed/31010855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811173
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