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Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome
The germinal center (GC) reaction in Peyer′s patches (PP) requires continuous access to antigens, but how this is achieved is not known. Here we show that activated antigen-specific CCR6(+)CCR1(+)GL7(−) B cells make close contact with M cells in the subepithelial dome (SED). Using in situ photoactiv...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547658/ https://ncbi.nlm.nih.gov/pubmed/31160559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10144-w |
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