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Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome
The germinal center (GC) reaction in Peyer′s patches (PP) requires continuous access to antigens, but how this is achieved is not known. Here we show that activated antigen-specific CCR6(+)CCR1(+)GL7(−) B cells make close contact with M cells in the subepithelial dome (SED). Using in situ photoactiv...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547658/ https://ncbi.nlm.nih.gov/pubmed/31160559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10144-w |
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