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N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation

The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif. The precise...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: MacNeil, Deanna E, Lambert-Lanteigne, Patrick, Autexier, Chantal
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547437/
https://ncbi.nlm.nih.gov/pubmed/30931479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz233
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