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N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation
The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif. The precise...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547437/ https://ncbi.nlm.nih.gov/pubmed/30931479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz233 |
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