Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1β Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation

Uncontrolled inflammation may produce massive inflammatory cytokines, in which interleukin 1β (IL-1β) plays a key role, resulting in tissue damage and serious disorders. The activation of NLRP3 inflammasome is one of the major mechanisms in maturation and release of IL-1β. Plectranthus amboinicus is...

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Sparad:
Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Leu, Wohn-Jenn, Chen, Jui-Ching, Guh, Jih-Hwa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546882/
https://ncbi.nlm.nih.gov/pubmed/31191313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00573
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