Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling

The nuclear protein DEK is an endogenous DNA-binding chromatin factor regulating hematopoiesis. DEK is one of only 2 known secreted nuclear chromatin factors, but whether and how extracellular DEK regulates hematopoiesis is not known. We demonstrated that extracellular DEK greatly enhanced ex vivo e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Capitano, Maegan L., Mor-Vaknin, Nirit, Saha, Anjan K., Cooper, Scott, Legendre, Maureen, Guo, Haihong, Contreras-Galindo, Rafael, Kappes, Ferdinand, Sartor, Maureen A., Lee, Christopher T., Huang, Xinxin, Markovitz, David M., Broxmeyer, Hal E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546479/
https://ncbi.nlm.nih.gov/pubmed/31107242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127460
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados