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Determinants of dopaminergic neuron loss in Parkinson’s disease
The cardinal motor symptoms of Parkinson’s disease (PD) are caused by the death of dopaminergic neurons in the substantia nigra pars compacta (SNc). Alpha-synuclein (aSYN) pathology and mitochondrial dysfunction have been implicated in PD pathogenesis, but until recently it was unclear why SNc dopam...
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| Publicado no: | FEBS J |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546423/ https://ncbi.nlm.nih.gov/pubmed/30028088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14607 |
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