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Boosting AgoshRNA activity by optimized 5’-terminal nucleotide selection
RNA interference (RNAi) can be triggered by synthetic small interfering RNAs (siRNAs) or transgene-expressed short hairpin RNAs (shRNAs). Recent evidence indicates that shRNA molecules, with a relatively short stem and small loop, are processed by Argonaute 2 protein (Ago2). We named these molecules...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546398/ https://ncbi.nlm.nih.gov/pubmed/30991896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1599259 |
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