Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems

Trans-activating CRISPR (tracr) RNA is a distinct RNA species that interacts with the CRISPR (cr) RNA to form the dual guide (g) RNA in type II and subtype V-B CRISPR-Cas systems. The tracrRNA-crRNA interaction is essential for pre-crRNA processing as well as target recognition and cleavage. The tra...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Faure, Guilhem, Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Crawley, Alexandra B., Barrangou, Rodolphe, Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546382/
https://ncbi.nlm.nih.gov/pubmed/30103650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1493331
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