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The Francisella novicida Cas12a is sensitive to the structure downstream of the terminal repeat in CRISPR arrays
The Class 2 Type V-A CRISPR effector protein Cas12a/Cpf1 has gained widespread attention in part because of the ease in achieving multiplexed genome editing, gene regulation, and DNA detection. Multiplexing derives from the ability of Cas12a alone to generate multiple guide RNAs from a transcribed C...
Tallennettuna:
| Julkaisussa: | RNA Biol |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546362/ https://ncbi.nlm.nih.gov/pubmed/30252595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1526537 |
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