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DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens

MOTIVATION: The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) nuclease system has allowed for high-throughput, large scale pooled screens for functional genomic studies. To aid in the translation of functional genomics to therapeutics, we developed DrugTh...

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Publicat a:Bioinformatics
Autors principals: Canver, Matthew C, Bauer, Daniel E, Maeda, Takahiro, Pinello, Luca
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546128/
https://ncbi.nlm.nih.gov/pubmed/30395160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty913
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