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Discovering and Mapping the Modified Nucleotides That Comprise the Epitranscriptome of mRNA

An important mechanism of gene expression regulation is the regulated modification of nucleotides in messenger RNA (mRNA). These modified nucleotides affect mRNA translation, stability, splicing, and other processes. A cluster of nucleotide modifications is found adjacent to the mRNA cap structure a...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Biol
Main Authors: Linder, Bastian, Jaffrey, Samie R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546050/
https://ncbi.nlm.nih.gov/pubmed/31160350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032201
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