In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure

Resistin (RETN) is a gene coding for proinflammatory adipokine called resistin secreted by macrophages in humans. Single nucleotide polymorphisms (SNPs) in RETN are linked to obesity and insulin resistance in various populations. Using dbSNP, 78 nonsynonymous SNPs (nsSNPs) were retrieved and tested...

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Veröffentlicht in:J Diabetes Res
Hauptverfasser: Elkhattabi, Lamiae, Morjane, Imane, Charoute, Hicham, Amghar, Soumaya, Bouafi, Hind, Elkarhat, Zouhair, Saile, Rachid, Rouba, Hassan, Barakat, Abdelhamid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545779/
https://ncbi.nlm.nih.gov/pubmed/31236417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4951627
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