Computational Analysis of nsSNPs of ADA Gene in Severe Combined Immunodeficiency Using Molecular Modeling and Dynamics Simulation

Severe combined immunodeficiency (SCID) is the most severe form of primary immunodeficiency (PID), characterized by fatal opportunistic infections. The ADA gene encodes adenosine deaminase, an enzyme that catalyzes the irreversible deamination of adenosine and deoxyadenosine in the catabolic pathway...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Essadssi, Soukaina, Krami, Al Mehdi, Elkhattabi, Lamiae, Elkarhat, Zouhair, Amalou, Ghita, Abdelghaffar, Houria, Rouba, Hassan, Barakat, Abdelhamid
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875294/
https://ncbi.nlm.nih.gov/pubmed/31781678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5902391
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