Prediction and Structural Comparison of Deleterious Coding Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Human LEP Gene Associated with Obesity

Leptin is a peptide hormone that regulates fat stores in the body and appetite by controlling the feeling of satiety. This hormone is secreted by the white adipose tissue and plays a role in the storage and mobilization of fatty acids. Mutations of the LEP gene have been associated with obesity in d...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Bouafi, Hind, Bencheikh, Sara, Mehdi Krami, AL, Morjane, Imane, Charoute, Hicham, Rouba, Hassan, Saile, Rachid, Benhnini, Fouad, Barakat, Abdelhamid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913293/
https://ncbi.nlm.nih.gov/pubmed/31871931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1832084
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