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Illumina error correction near highly repetitive DNA regions improves de novo genome assembly

BACKGROUND: Several standalone error correction tools have been proposed to correct sequencing errors in Illumina data in order to facilitate de novo genome assembly. However, in a recent survey, we showed that state-of-the-art assemblers often did not benefit from this pre-correction step. We found...

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Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Heydari, Mahdi, Miclotte, Giles, Van de Peer, Yves, Fostier, Jan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545690/
https://ncbi.nlm.nih.gov/pubmed/31159722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2906-2
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