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Evaluation of the impact of Illumina error correction tools on de novo genome assembly

BACKGROUND: Recently, many standalone applications have been proposed to correct sequencing errors in Illumina data. The key idea is that downstream analysis tools such as de novo genome assemblers benefit from a reduced error rate in the input data. Surprisingly, a systematic validation of this ass...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Heydari, Mahdi, Miclotte, Giles, Demeester, Piet, Van de Peer, Yves, Fostier, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563063/
https://ncbi.nlm.nih.gov/pubmed/28821237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1784-8
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