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CRAC Channels And Disease – From Human CRAC Channelopathies And Animal Models To Novel Drugs

Ca(2+) release-activated Ca(2+) (CRAC) channels are intimately linked with health and disease. The gene encoding the CRAC channel, ORAI1, was discovered in part by genetic analysis of patients with abolished CRAC channel function. And patients with autosomal recessive loss-of-function (LOF) mutation...

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Detalhes bibliográficos
Publicado no:Cell Calcium
Autor principal: Feske, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545165/
https://ncbi.nlm.nih.gov/pubmed/31009822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2019.03.004
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