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A severe defect in CRAC Ca(2+) channel activation and altered K(+) channel gating in T cells from immunodeficient patients
Engagement of the TCR triggers sustained Ca(2+) entry through Ca(2+) release-activated Ca(2+) (CRAC) channels, which helps drive gene expression underlying the T cell response to pathogens. The identity and activation mechanism of CRAC channels at a molecular level are unknown. We have analyzed ion...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212870/ https://ncbi.nlm.nih.gov/pubmed/16147976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050687 |
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