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The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency

BACKGROUND: Small nucleolar RNA host gene 3 (Snhg3) is a long non-coding RNA (lncRNA) that was shown to participate in the tumorigenesis of certain cancers. However, little is known about its role in embryonic stem cells (ESCs). METHODS: Here, we investigated the role of Snhg3 in mouse ESCs (mESCs)...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Lu, Weisi, Yu, Jianping, Shi, Fengtao, Zhang, Jianing, Huang, Rui, Yin, Shanshan, Songyang, Zhou, Huang, Junjiu
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545032/
https://ncbi.nlm.nih.gov/pubmed/31151411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1270-5
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