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ICA512 RESP18 homology domain is a protein-condensing factor and insulin fibrillation inhibitor
Type 1 diabetes islet cell autoantigen 512 (ICA512/IA-2) is a tyrosine phosphatase–like intrinsic membrane protein involved in the biogenesis and turnover of insulin secretory granules (SGs) in pancreatic islet β-cells. Whereas its membrane-proximal and cytoplasmic domains have been functionally and...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544868/ https://ncbi.nlm.nih.gov/pubmed/30979722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007607 |
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