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H(2)O(2) induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism
Reactive oxygen species (ROS) are cellular by-products produced from metabolism and also anticancer agents, such as ionizing irradiation and chemotherapy drugs. The ROS H(2)O(2) has high rates of production in cancer cells because of their rapid proliferation. ROS oxidize DNA, protein, and lipids, c...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544865/ https://ncbi.nlm.nih.gov/pubmed/30962283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005953 |
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