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H(2)O(2) induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism

Reactive oxygen species (ROS) are cellular by-products produced from metabolism and also anticancer agents, such as ionizing irradiation and chemotherapy drugs. The ROS H(2)O(2) has high rates of production in cancer cells because of their rapid proliferation. ROS oxidize DNA, protein, and lipids, c...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Chen, Mei-Kuang, Du, Yi, Sun, Linlin, Hsu, Jennifer L., Wang, Yu-Han, Gao, Yuan, Huang, Jiaxing, Hung, Mien-Chie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544865/
https://ncbi.nlm.nih.gov/pubmed/30962283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005953
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