Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

Multiple Sclerosis (MS) is characterised by an immune system attack targeting myelin, which is produced by oligodendrocytes (OLs). We performed single-cell transcriptomic analysis of OL lineage cells from the spinal cord of mice induced with experimental autoimmune encephalomyelitis (EAE), which mim...

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Udgivet i:Nat Med
Main Authors: Falcão, Ana Mendanha, van Bruggen, David, Marques, Sueli, Meijer, Mandy, Jäkel, Sarah, Agirre, Eneritz, Samudyata, Floriddia, Elisa M., Vanichkina, Darya P., ffrench-Constant, Charles, Williams, Anna, Guerreiro-Cacais, André Ortlieb, Castelo-Branco, Gonçalo
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544508/
https://ncbi.nlm.nih.gov/pubmed/30420755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0236-y
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