Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

Oligodendrocytes have been considered as a functionally homogenous population in the central nervous system (CNS). We performed single-cell RNA-Seq on 5072 cells of the oligodendrocyte lineage from ten regions of the mouse juvenile/adult CNS. Twelve populations were identified, representing a contin...

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Pubblicato in:Science
Autori principali: Marques, Sueli, Zeisel, Amit, Codeluppi, Simone, van Bruggen, David, Mendanha Falcão, Ana, Xiao, Lin, Li, Huiliang, Häring, Martin, Hochgerner, Hannah, Romanov, Roman A., Gyllborg, Daniel, Muñoz Manchado, Ana, La Manno, Gioele, Lönnerberg, Peter, Floriddia, Elisa M., Rezayee, Fatemah, Ernfors, Patrik, Arenas, Ernest, Hjerling-Leffler, Jens, Harkany, Tibor, Richardson, William D., Linnarsson, Sten, Castelo-Branco, Gonçalo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221728/
https://ncbi.nlm.nih.gov/pubmed/27284195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf6463
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