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Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity

The murine epidermis with its hair follicles represents an invaluable model system for tissue regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal how cellular heterogeneity of murine telogen epidermis is tuned at the transcriptional level. Unbiased clustering of 1,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Syst
Hauptverfasser: Joost, Simon, Zeisel, Amit, Jacob, Tina, Sun, Xiaoyan, La Manno, Gioele, Lönnerberg, Peter, Linnarsson, Sten, Kasper, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052454/
https://ncbi.nlm.nih.gov/pubmed/27641957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.08.010
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