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Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity

The murine epidermis with its hair follicles represents an invaluable model system for tissue regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal how cellular heterogeneity of murine telogen epidermis is tuned at the transcriptional level. Unbiased clustering of 1,...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Joost, Simon, Zeisel, Amit, Jacob, Tina, Sun, Xiaoyan, La Manno, Gioele, Lönnerberg, Peter, Linnarsson, Sten, Kasper, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052454/
https://ncbi.nlm.nih.gov/pubmed/27641957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.08.010
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