PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

Citrullination, the deimination of peptidylarginine residues into peptidylcitrulline, has been implicated in the etiology of several diseases. In multiple sclerosis, citrullination is thought to be a major driver of pathology through hypercitrullination and destabilization of myelin. As such, inhibi...

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Publicado no:Cell Rep
Main Authors: Falcão, Ana Mendanha, Meijer, Mandy, Scaglione, Antonella, Rinwa, Puneet, Agirre, Eneritz, Liang, Jialiang, Larsen, Sara C., Heskol, Abeer, Frawley, Rebecca, Klingener, Michael, Varas-Godoy, Manuel, Raposo, Alexandre A.S.F., Ernfors, Patrik, Castro, Diogo S., Nielsen, Michael L., Casaccia, Patrizia, Castelo-Branco, Gonçalo
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486480/
https://ncbi.nlm.nih.gov/pubmed/31018126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.108
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