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Hydroxy group-enabled highly regio- and stereo-selective hydrocarboxylation of alkynes

Here we present an example of utilizing hydroxy groups for regioselectivity control in the addition reaction of alkynes—a highly efficient Pd-catalyzed syn-hydrocarboxylation of readily available 2-alkynylic alcohols with CO in the presence of alcohols with an unprecedented regioselectivity affordin...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Huang, Chaofan, Qian, Hui, Zhang, Wanli, Ma, Shengming
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544123/
https://ncbi.nlm.nih.gov/pubmed/31293734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05743e
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