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An evolutionary framework for measuring epigenomic information and estimating cell-type specific fitness consequences
Here, we ask the question, “How much information do epigenomic data sets provide about human genomic function?” We consider nine epigenomic features across 115 cell types and measure information about function as a reduction in entropy under a probabilistic evolutionary model fitted to human and non...
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| 出版年: | Nat Genet |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544027/ https://ncbi.nlm.nih.gov/pubmed/30559490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0300-z |
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