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Whole-Exome Sequencing Enables the Diagnosis of Variant-Type Xeroderma Pigmentosum

BACKGROUND: Xeroderma pigmentosum (XP) is a rare autosomal, recessive, inherited disease. XP patients exhibit high sensitivity to sunlight and increased incidence of skin cancer. The different XP subtypes, which are caused by mutations of eight distinct genes, show some specific clinical manifestati...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Fang, Xiaokai, Sun, Yonghu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543889/
https://ncbi.nlm.nih.gov/pubmed/31178899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00495
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