Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

BACKGROUND: Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are largely unknown. In that context, profiling DNA methylation, which is a stable and cell type-specific regulatory epigenetic mark...

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Dades bibliogràfiques
Publicat a:Clin Epigenetics
Autors principals: Kular, Lara, Needhamsen, Maria, Adzemovic, Milena Z., Kramarova, Tatiana, Gomez-Cabrero, David, Ewing, Ewoud, Piket, Eliane, Tegnér, Jesper, Beck, Stephan, Piehl, Fredrik, Brundin, Lou, Jagodic, Maja
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543588/
https://ncbi.nlm.nih.gov/pubmed/31146783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0678-1
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