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Long‐term cardiovascular effects of vandetanib and pazopanib in normotensive rats

Vandetanib and pazopanib are clinically available, multi‐targeted inhibitors of vascular endothelial growth factor (VEGF) and platelet‐derived growth factor (PDGF) receptor tyrosine kinases. Short‐term VEGF receptor inhibition is associated with hypertension in 15%‐60% of patients, which may limit t...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Cooper, Samantha L., Carter, Joanne J., March, Julie, Woolard, Jeanette
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543457/
https://ncbi.nlm.nih.gov/pubmed/31164986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.477
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