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Cardiovascular responses to retigabine in conscious rats – under normotensive and hypertensive conditions

BACKGROUND AND PURPOSE: Retigabine is a recently approved antiepileptic agent which activates K(v)7.2–7.5 potassium channels. It is emerging that these channels have an important role in vascular regulation, but the vascular effects of retigabine in the conscious state are unknown. Hence, in the pre...

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Autors principals: Fretwell, L V, Woolard, J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831708/
https://ncbi.nlm.nih.gov/pubmed/23581476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12203
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