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CXCR4 in human osteosarcoma malignant progression. The response of osteosarcoma cell lines to the fully human CXCR4 antibody MDX1338

Osteosarcoma (OS) is the most frequent primary malignant tumour of bone and metastases occur in 30% of cases, the 5-year survival rate is 25–30%. Although pre- and post-operative chemotherapy has improved prognosis in osteosarcoma (OS), high toxicity and natural and acquired drug-resistance are the...

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Bibliografiske detaljer
Udgivet i:J Bone Oncol
Main Authors: Pollino, Serena, Palmerini, Emanuela, Dozza, Barbara, Bientinesi, Elisa, Piccinni-Leopardi, Martina, Lucarelli, Enrico, Righi, Alberto, Benassi, Maria Serena, Pazzaglia, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543022/
https://ncbi.nlm.nih.gov/pubmed/31193811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100239
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