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Evaluating the effects of design parameters on the performances of phase I trial designs
Numerous designs have been proposed for phase I clinical trials. Although studies have compared their performances, few have considered the effects of changing design parameters. In this article, we review a few popular designs, including the 3 + 3, continuous reassessment method (CRM), Bayesian opt...
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| 出版年: | Contemp Clin Trials Commun |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6543020/ https://ncbi.nlm.nih.gov/pubmed/31193764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100379 |
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