Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer

Many signaling pathways, including the JAK/STAT3 pathway, are aberrantly activated and associated with ovarian cancer growth and progression. However, inhibition of STAT3 pathway alone was not sufficient to effectively block human ovarian cancer cell survival in vitro, which could be due to the acti...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Wen, Wei, Han, Ernest S., Dellinger, Thanh H., Wu, Jun, Guo, Yuming, Buettner, Ralf, Horne, David A., Jove, Richard, Yim, John H.
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2019
Fag:
Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542771/
https://ncbi.nlm.nih.gov/pubmed/31141756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.05.003
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