Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment

Although cardiovascular disease (CVD) is the leading cause of morbimortality worldwide, promising new drug candidates are lacking. We compared the arterial high-resolution proteome of patients with advanced versus early-stage CVD to predict, from a library of small bioactive molecules, drug candidat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Schanstra, Joost P., Luong, Trang T.D., Makridakis, Manousos, Van Linthout, Sophie, Lygirou, Vasiliki, Latosisnska, Agnieszka, Alesutan, Ioana, Boehme, Beate, Schelski, Nadeshda, Von Lewinski, Dirk, Mullen, William, Nicklin, Stuart, Delles, Christian, Feuillet, Guylène, Denis, Colette, Lang, Florian, Pieske, Burkert, Bascands, Jean-Loup, Mischak, Harald, Saulnier-Blache, Jean-Sebastien, Voelkl, Jakob, Vlahou, Antonia, Klein, Julie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542631/
https://ncbi.nlm.nih.gov/pubmed/31092728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125638
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