Connectivity mapping of glomerular proteins identifies dimethylaminoparthenolide as a new inhibitor of diabetic kidney disease

While blocking the renin angiotensin aldosterone system (RAAS) has been the main therapeutic strategy to control diabetic kidney disease (DKD) for many years, 25–30% of diabetic patients still develop the disease. In the present work we adopted a systems biology strategy to analyze glomerular protei...

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הוצא לאור ב:Sci Rep
Main Authors: Klein, Julie, Caubet, Cécile, Camus, Mylène, Makridakis, Manousos, Denis, Colette, Gilet, Marion, Feuillet, Guylène, Rascalou, Simon, Neau, Eric, Garrigues, Luc, Thillaye du Boullay, Olivier, Mischak, Harald, Monsarrat, Bernard, Burlet-Schiltz, Odile, Vlahou, Antonia, Saulnier-Blache, Jean Sébastien, Bascands, Jean-Loup, Schanstra, Joost P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2020
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484761/
https://ncbi.nlm.nih.gov/pubmed/32913274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71950-7
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