SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Modified vaccinia virus Ankara (MVA) is the leading poxvirus vector for development of vaccines against diverse infectious diseases. This distinction is based on high expression of proteins and good immunogenicity despite an inability to assemble infectious progeny in human cells, which together pro...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Liu, Ruikang, Mendez-Rios, Jorge D., Peng, Chen, Xiao, Wei, Weisberg, Andrea S., Wyatt, Linda S., Moss, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542542/
https://ncbi.nlm.nih.gov/pubmed/31145755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007710
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